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Actiferon is a slow release iron tablets which are easy to swallow and easy on stomach it is rich in iron combining folic acid and physiologically active vitamin B-12 and zinc in delayed release form avoiding the inhibition of iron absorption. Iron in the form of ferrous ascorbate is highly bioavailable as ferrous ion is absorbed three times more than ferric ion in the alkaline PH of intestine . ACTIFERON contains complete folic acid to support the deficiency during pregnancy . Three hour delayed release of zinc corrects the zinc deficiency during pregnancy , without effecting iron absorption.
Each tablet contains (approx.)
Ferrous bisglycinate* Equivalent to Elemental Iron - 60mg
Adenosylcobalamin - 150mcg
Methylcobalamin - 150mcg
L-Methylfolate calcium - 400mcg
Pyridoxal 5 phosphate - 2.5mg
Zinc bisglycinate - 15mg
* Prolonged release
Suggested use : 1-2 tablets a day or as directed by the healthcare practitioner.
Storage : Store in a cool, dry & dark place. Keep out of reach of children.
Dietary Supplement. Not for medicinal use.
Side effects: nil
Contra-Indications: Hemosiderosis, Hemochromatosis, Hemolytic anaemia.
Precautions: Oral Multinutrient iron preparations may aggravate existing peptic ulcer, regional enteritis and ulcerative colitis. Iron compounds taken orally can impair the absorption of tetracycline antibiotics. Antacids given concomitantly with iron compounds decrease iron absorption.
Adverse Reactions: The treatment of a neurotic patient was interrupted because of nausea and regurgitation. In pregnant women, the incidence of pyrosis and chronic constipation is slightly increased. In children, a clinical investigator reported 3 cases of slight diarrhea which disappeared within a few days. In 1 case, slightly curdled stools were observed, although this could not be definitely attributed to the product. In the final case studies, clay colored stools was noted.
Symptoms and Treatment of Overdose: Iron poisoning is rare in adults but serious acute poisoning in children can result from ingestion of doses in excess of 1g. Doses of 1 g should be considered as toxic in children and therapy instituted as soon as possible. Serum iron levels above 500 µg/100ml can be taken as presumptive evidence of poisoning: severe poisoning is usually associated with levels well above 1000µg/100 ml.
SYMPTOMS: May occur within 30 minutes or may be delayed several hours. They are largely those of gastrointestinal irritation and necrosis with vomiting, diarrhea, tarry stools, hematemesis, fast and weak pulse, lethargy, low blood pressure, coma and signs of peripheral circulatory commapse. There may be transient period of apparent recovery after 4 to 6 hours followed by a second crisis characterized by cyanosis, pulmonary edema, circulatory collapse, convulsion, and coma may then occur followed by death in 12 to 48 hours.
TREATMENT: Milk should be given immediately and vomiting induced. Eggs and milk should be fed (to form iron-protein complexes) until it is possible to perform gastric lavage with 1% sodium bicarbonate solution (to convert the iron to a less soluble form). Gastric lavage should not be performed after the first hour of iron ingestion because of the danger of perforation due to gastric necrosis. If an iron-chelating agent such as deferoxamine mesylate is available, it should be utilized. BAL (dimercaprol) should not be used because it may form a toxic compiled. Measures to combat shock, dehydration, blood loss and respiratory failure may be necessary.
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